Quiz 34: So what are the objective results of treatment with testosterone?

Quiz Summary

0 of 8 questions completed

Questions:

You have already completed this quiz. You cannot start it again.

Quiz is loading…

You must sign in or sign up to take this quiz.

You must first complete the following:

Results

Quiz complete. Results are being recorded.

Results

0 of 8 questions answered correctly

Your Time:

You have reached 0 of 0 point(s), (0)

Average Score
Your Score

Your grade: F
Your grade: D
Your grade: D+
Your grade: C-
Your grade: C
Your grade: C+
Your grade: B-
Your grade: B
Your grade: B+
Your grade: A-
Your grade: A
Your grade: A+

Current
Review
Answered
Correct
Incorrect

Question 1 of 8

1. Question
Testosterone therapy in 100 cases of angina pectoris (choose correct answer):
- Study in 1946: Testosterone therapy improved symptoms and exercise tolerance in 91 of 100 patients with angina pectoris, 51 markedly
- None of 7 placebo controls responded, all of whom later responded to testosterone
- 10 other studies were reviewed showing similar results
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 2 of 8

2. Question
Low-dose transdermal testosterone therapy improves angina threshold in men with chronic stable angina: A randomized, double-blind, placebo-controlled study (choose correct answer):
- 46 men with stable angina were given a 5 mg testosterone patch for 12 weeks in a double-blind study
- There was a significant increase in time to 1 mm ST segment depression from 306 +/- 27 to 366 +/- 22
- There was a greater improvement in the individuals with the lowest initial levels of testosterone
- There were no significant changes in lipids, hemostatic factors, hemoglobin, or PSA
- The more severe the angina and its causes, the less the responsiveness to testosterone
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 3 of 8

3. Question
Anti-Ischemic Effect of Acute Testosterone Administration in Men With Coronary Artery Disease (choose correct answer):
- Study: Acute administration of testosterone on exercise-induced myocardial ischemia in 12 men aged 58 ± 4 years with proven CAD
- Testosterone 2.5 mg IV given prior to Stress EKG
- Normalization of Stress EKG in 9
- Time to 1 mm ST segment depression, the first indicator of ischemia, and total exercise time were increased by 1 minute
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 4 of 8

4. Question
Acute administration of testosterone in CAD (choose correct answer):
- IV administration of testosterone to men with documented CAD increases time to ischemic changes during treadmill testing
- Time to ischemia increased by 66 sec (22%)
- Interestingly, of the original cohort of 139, 52% had severely deficient testosterone levels
- An unstated conclusion of the study might be that frequently occurring testosterone deficiency in patients with CAD is undiagnosed and untreated
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 5 of 8

5. Question
The pharmacokinetics of intravenous testosterone in elderly men with coronary artery disease (choose correct answer):
- Intravenous testosterone is rapidly converted into E2 after only 5 minutes and is maintained during administration over 3 hours
- Vasodilatory effects of testosterone involve both direct and indirect mechanisms, including conversion to E2
- Nitric oxide synthase is both estrogen- and testosterone-dependent in selected arteries
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 6 of 8

6. Question
Effect of dihydrotestosterone treatment on exercise induced ischemia in men with stable ischemic heart disease (choose correct answer):
- 12-week controlled study of transdermal DHT hormone replacement in hypogonadal males with stable CAD
- Chronic DHT administration increased significantly – total exercise time, time to the onset of angina, and time to 1 mm ST depression
- The changes of heart rate and systolic blood pressure indicate rather direct coronary-relaxing effect of DHT than peripheral one
- DHT can be converted to estrogen so that the beneficial effect again might be due to the increase in estrogen
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 7 of 8

7. Question
Testosterone treatment in CHF (choose correct answer):
- 20 males with CHF randomized, double-blind, placebo-controlled study over 12 weeks
- Testosterone (Sustanon) 100 mg IM biweekly for 12 weeks (low dose)
- Testosterone improved overall exercise time in the shuttle walk test (SWT) 91 m vs 21 m (p 0.018)
- There was improvement in MLHF heart failure symptom scores
- Reduced BNP in the treatment group – -9.3 (17.6) vs 4.5 (10.9) – p = 0.063
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect
Question 8 of 8

8. Question
Key facts to remember on testosterone – heart disease (choose correct answer):
- There are more testosterone receptors in the heart than any other muscle
- Low testosterone correlates with almost every major risk factor for CAD
- Correction of the deficiency is associated with reduction of most risk factors and improved physiology
- Most treatment studies to date report improved function and objective EKG changes
- All of the above are correct
- One of the above is incorrect
Correct

Incorrect

Andropause Mastery

Quiz 34: So what are the objective results of treatment with testosterone?

Quiz Summary

Information

Results

Results

Categories

Your grade: F

Your grade: D

Your grade: D+

Your grade: C-

Your grade: C

Your grade: C+

Your grade: B-

Your grade: B

Your grade: B+

Your grade: A-

Your grade: A

Your grade: A+

1. Question

2. Question

3. Question

4. Question

5. Question

6. Question

7. Question

8. Question